Contrave is a prescription weight loss pill made to deliver results through appetite suppression. It’s a combination of 2 ingredients which were originally used as an anti-depressant and drug and alcohol addiction treatment.
In order to use this drug you must introduce diet and exercise. It’s also necessary to have a body mass index of 30 or above. If you have an obesity related illnesses you can also take this brand if you have a BMI of at least 27. Before using this drug a doctor has to establish that a person qualifies and isn’t susceptible to the numerous potential side effects. So is there any significant weight loss possible? What kind of use does this brand have for someone looking to lose weight? This full Contrave review has the information you need to know.
Bupropion: Antidepressant drug also used to reduce appetite. In the US and Canada it’s the number one prescribed antidepressant. This drug has shown very little weight loss benefits. In one clinical study it showed just over 5 pounds of weight loss after being used for a full year. It can potentially lead to the following side effects:
Naltrexone: Used as a way to block the effects of alcohol and narcotics in people who are addicted. It’s most commonly used as a way to block opioid drugs. There have been numerous reported side effects:
Inactive ingredients include:
|Microcrystalline Cellulose||Hydroxypropyl Cellulose||Lactose Anhydrous||L-cysteine hydrochloride|
|Crospovidone||Magnesium Stearate||Hypromellose||Edetate Disodium|
|Lactose Monohydrate||Colloidal Silicon Dioxide||Opadry 2 Blue||FD&C Blue #2 Lake|
Lactose Anhydrous: A nonnutritive ingredient used as filler to increase size. Since it contains lactose, people that are lactose intolerant are advised to avoid it.
Edetate Disodium: Used to remove heavy metals such as lead in an ingredient mixture. It’s also used to reduce calcium in the blood when they are in dangerous limits. It’s unknown why this ingredient is added to this mix, or if there’s potential contaminants such as heavy metals added.
FD&C Blue #2 Lake: Simply added to give Contrave a blue color. This food additive has no nutritional value. Rats fed this ingredient had significant increases of brain cancer. The Center for Science in the Public Interest has tried to ban this ingredient due to its potential for serious side effects. It has also been linked to hyperactivity in children.
When mixing both of these drugs together the intended benefit is supposed to be change in the brain. The change is supposed to make food less rewarding in the brain, which is supposed to reduce food addiction.
This drug has been linked to:
Each box of Contrave is required to have these warnings listed.
The drugs work in combination by hitting areas in the central nervous system. Due to the uncertainty of what kind of an effect this may have on the body, a doctor has to ensure that one is healthy and at a certain level of obesity.
Since the side effects can be deadly, there’s too much risk for an unguaranteed result.
It’s advised to slowly build up to this brand with one pill a day, after 4 weeks it’s recommended to take 4.
Also, the cost of this brand depends on where you get it from. Good RX.com mentions the list of the current prices for pharmacies. The lowest price is available for $216.55 for a 120 tablet bottle.
So the first 4 weeks will result in taking 70 pills. To calculate the cost after the body adjusts to four pills a day would equal:
$216.55/30= $7.21 for a daily serving.
There are a lot of restrictions one has to abide by. Such as keeping fat intake low in order to prevent seizures, and telling your doctor if you’re not losing enough weight.
Since there’s no guarantee of safety or effectiveness, this brand may be a potentially risky and expensive pill.
Before a drug is introduced into the market, the FDA has to see that the clinical studies showed an effect.
This brand had major studies done on 4,500 obese people which the FDA looked over and approved. This still requires reduced calories and exercise as well as a high BMI.
The study showed a 4.1 drop in weight in one year. 42% of the people who partook lost at least 5% of their body fat.
To calculate the average, this means that a 200 pound person could lose 4.1 which are 8.2 pounds in one full year. This is also with diet and exercise, which alone can cause a drop in weight.
In a major clinical study on Contrave published in Pub Med it was advised that:
“dietary and lifestyle changes should always remain the first-line treatment of obesity.”
The company does mention to limit calories and include exercise. However, since the brand only shows about 4.1% fat loss in one year, diet and exercise alone could contribute to much more changes.
Before being considered for Contrave you cannot have a history of or are:
Also, if you have any of the following it’s advised to tell a doctor:
You also have to keep close contact with a physician since there’s very unique things about this drug. For example, you can’t eat high fat meals with this drug since it greatly increases the chance for seizures. Avoiding alcohol is also recommended as it can lead to dangerous side effects.
Takeda Pharmaceuticals from Japan own this brand. Their US customer service can be reached below:
Phone Number: (224) 554-6500
Address: 1 Takeda Pkwy
Deerfield, Illinois 60015
They were subject to 2 major lawsuits:
There are many reviews available on Drugs.com:
“There are better, less toxic symptoms”
“Worsened heart problems”
“I had horrible constipation”
“It made me sick as a dog, I couldn’t think correctly”
There are many customers mentioning how they didn’t lose weight, some that did add that they couldn’t continue due to the side effects. The effects of nausea were too much to stomach further use. When taking this brand it’s advised to stop taking it altogether and to watch out for dosing.
Here are the important details to remember about Contrave:
Due to the high rate of unsatisfied customers and the long list of potential side effects, Contrave isn’t the best weight loss pill available.
It’s also very expensive at the lowest pharmacy price of $212.55 for one bottle. There’s also no guarantee that you’ll be able to lose any weight.
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