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Health Guide Review: 3,1/5


Phen375 Review: Does it work?

Intro: What is it?

Phen375 is a weight loss pill claiming to be pharmacy quality and able to burn fat daily. It’s made to increase metabolism, reduce food cravings, and to metabolize fats.

It’s advised that in order to properly lose weight one should increase exercise while reducing up to 500 calories each day. The company adds that health experts agree this is the safe way to reduce about a pound a week. It’s suggested that with Phen375 you’ll be able to improve overall results. Is there any positive effect to all this? What kinds of results are possible? This full Phen375 review has all the information you need to know.

Phen375 Ingredients

Calcium Carbonate Chromium (Picolinate) L-Carnitine Tartrate Citrus Aurantium extract standardized for 10% Synephrine
Caffeine Anhydrous Cayenne(Capsicum) Dendrobrium Nobile Extract (from orchids) Coleus Forskohlii Root PE 10% Foskolin


The company fails to provide any full supplements facts list, so it’s unknown if these are the only ingredients or if there’s additional additives. Many times brands will have inactive ingredients such as food coloring or fillers that can be potentially dangerous.

Different websites claim to offer a supplements facts list, but each site offers different amounts. This is potentially dangerous and it doesn’t allow for one to accurately judge the ingredient dosages. Especially when ingredients like Caffeine are added, it’s important to know what the right amount is. Here are the company mentioned ingredients worth looking into:

Citrus Aurantium: Used as a natural stimulant and appetite suppressant. The key active ingredient is Synephrine, which raises heart rate and blood pressure. It’s also linked to:

  • Anxiety, rapid heart rate, and feelings of paranoia.
  • Insomnia, restlessness, and inability to focus.
  • Chest pain and pressure.
  • Migraines and headaches.
  • Inflammation and injury to the large intestine.
  • Heart attack and stroke.

According to Web MD it’s:

POSSIBLY UNSAFE when taken as a supplement”

“Increases the risk for…severe side effects.”

These risks for side effects are increased even further when it’s mixed with caffeine. One clinical study in particular showed that a once healthy young man who took this ingredient suffered from a serious heart attack. He had no history of heart attacks in his family, so it was blamed on the bitter orange he took.

Caffeine Anhydrous: Dehydrated caffeine used to simulant the body leading to an increase in mental focus and physical energy. High amounts of caffeine can lead to dependence and withdrawal symptoms as well as side effects including:

  • Increased blood pressure.
  • Reduced bone minerals in women.
  • Tremors, muscle twitching, and jitters.
  • Insomnia and restlessness.
  • Nausea and indigestion.
  • Chest pains and palpitations.

Caffeine is often used as a way to increase fat burning.  The American Journal of Physiology noted that habitual use of caffeine reduces any of its benefits for weight loss, they mention:

“you may become less sensitive to its effects”

Coleus Forskohlii: Herb used as a testosterone and fat loss booster.  More studies are needed to prove these effects.

L-Carnitine Tartrate: Found in both foods and naturally produced in the body, this ingredient helps create energy and burn fat. In supplement form studies have shown it to be ineffective. According to L-Carnitine Tartrate:

do(es) not show very good results.”

In supplement form it can also lead to side effects:

  • Stomach pains.
  • Nausea and vomiting.
  • Gastrointestinal issues including diarrhea.

Dendrobrium Nobile Extract: Extracted from the Orchid flower. It’s used to reduce blood pressure and pain.  Web MD mentions that it hasn’t been well studied and that the:

effects of dendrobium in people are not clear.”

They also add it’s unknown what kind of side effects it may have.

Cayenne (Capsicum): Thermogenic extract added to increase metabolism. It’s what gives chili peppers its spice. mentions its results are limited:

“can burn body fat with minimal potency”

Potential side effects may include:

  • Stomach irritation and upset stomach.
  • Sweating and flushing skin.
  • Runny nose.
  • Liver or kidney damage.

Long term use in particular may produce damage to the organs.

Phen375 Quality of Ingredients

Without knowing the full ingredient listing or amounts its unknown if these additives are included in safe or effective amounts.

Some of these ingredients are potentially harmful. This is especially an issue with the mixture of caffeine anhydrous and bitter orange. This has been shown to cause heart problems and blood pressure rise.

The weak or ineffective ingredients include 3 which are Dendrobrium, Capsicum, and L-Carnitine Tartrate.

2 of the stimulants are potentially harmful, and the Calcium Carbonate and Chromium Picolinate are included in unknown amounts, so they may be ineffective or weak as well.

The Price and Quality of Phen375

One 30 tablet bottle costs $64.99 and their standard shipping id $10.

It’s unknown how many doses one needs to take, so assuming it’s a one a day the daily price is:

$74.99/30= $2.49 assuming its one daily serving.

They also mention:

cutting about 500 calories a day”

“exercising regularly”

As well as eating nutritious foods is a recommended way of losing a pound a week. They mention Phen375 helps assist this process, but they fail to add any evidence to show how much more of a benefit is gained. You can lose around a pound with a daily 500 calorie deficit, so it’s unknown where Phen375 comes in to support this and in what way.

Heavy Use of Stimulants

The National Center for Complementary and Integrative Health mentions that mixing caffeine with bitter orange is potentially unsafe.

They mention that bitter orange on its own has led to:

reports of fainting, heart attack, and stroke in healthy people”

Natural Medicines also adds:

caffeine and synephrine together may increase heart rhythm and blood pressure”

Certain people are more sensitive to these stimulants as well.

Determining whether or not this brand has a safe amount of these ingredients is impossible because they fail to add an ingredient label.  It’s unknown if this is provided when you order Phen375.

Unknown Ingredients

The manufactures fail to list the actual ingredient amounts; it’s also not specified exactly how much one needs to take of Phen375.

Without knowing the dosage strength and full ingredient profile it makes it impossible for a physician to judge whether or not this mixture if safe for specific people.

This is made even more complicated since the company offers no information about themselves. It’s unknown how if customers are satisfied since the majority of reviews are biased.

Knowing the specific amounts of ingredients is important since the company adds unknown amounts of caffeine and bitter orange, 2 potentially dangerous ingredients.

Dosage strengths in particular are needed to judge if you’re getting safe amounts of caffeine. This is around 400 mg for the average person, though some have more difficulty in using stimulants.

Though caffeine and bitter orange combine together to form an even more powerful stimulant mixture since they support each other’s effects.

Business of Phen375

The terms and conditions mention that the company is called the Shipitsa LTD company, and they are based out of Europe. Though they do hold a US office:

Phone Number: (855) 281-8098

Address: 3636 N. Buckner Blvd

Dallas, Texas 75228

No information exists about the company and when researching their name only the Phen375 website appeared.

The company does not offer a money back return unless it’s within 48 hours of receiving shipment.  This has to be done with a tracking number using priority mail, and with an undamaged, unopened bottle.

Customer Opinions of Phen375

Researching the real opinion behind this brand is hard because the company uses affiliates who earn a commission off sales.

Many websites claim to offer “Real Phen375 Reviews”, and there’ many online salesmen who claim this brand is the best for weight loss.

I couldn’t find one unbiased review which didn’t end with the person leaving behind their affiliate link.  So it’s unknown what the actual effects are from real customers.


The most important points to look at Phen375 are:

  • The lack of a useful money back guarantee: The length of the money back guarantee is not only expensive since you have to pay premium shipping, but it’s only for 48 hours of receiving the product. You can’t use it or tamper with it in any way. You also have to ensure the company receives a return number and you have to pay for the shipping on your own. This makes it impossible to know if you’ll have a favorable experience with Phen375. You have to decide within it shipping that you don’t want to try it. So if you have a bad experience you’re unable to get a return. At minimum you’re going to spend $74.99 for a 30 capsule bottle, and it’s unknown how long this bottle will last since the company does not list what the daily amount is.
  • It’s unknown what the ingredient strength is: No ingredients label is provided, so it’s unknown how much of each ingredient is included. There’s a mixture of two ingredients in particular in bitter orange and caffeine which are potentially dangerous on their own. When mixed together it raises the potential for side effects. It’s important to gauge exactly how much of each ingredient you‘re getting since each additive alone has been shown to potentially cause side effects. This makes it impossible for a physician to determine whether or not this brand is safe to take depending on your own health concerns.
  • Many of the ingredients are known to cause serious side effects: The unknown mixture of additives can potentially cause rapid heart rate, muscle tremors, insomnia, mood swings, cardiovascular damager, and organ failure. These are just some of the potential side effects. There’s a full list of possible negative symptoms one might face. It all depends on how well one handles the mixture. Taking stimulants too late in the day may also lead to further side effects. Also, cycling caffeine is important since its benefits are reduced after long term use.
  • No unbiased customer opinions are available: Since the company offers a commission off sales, many regular people will sell this brand online. Several salesmen have even made their own websites which claim to offer real reviews on Phen375. These people add an affiliate link where they can gain sales off any purchases. This makes it impossible to know if there are any real customers, since there wasn’t one website which had authentic reviews. So it’s unknown if it’s effective or whether or not side effects are common. Without looking at customer reviews the only way to determine if this brand is safe to use is by trying it, since no money back guarantee is offered on opened bottles. Relying on stimulants for weight loss is not a long term solution; since it’s been shown caffeine in particular loses its weight loss benefits after repeat use.
  • The company fails to provide any clinical studies: Though the company claims to provide a brand with weight loss and hunger suppression qualities under a FDA approved facility, it’s hard to fact check any of these claims. Stimulants do offer some appetite suppression and the potential for some weight loss, but it’s not anything long term. Also, this may be at the cost of side effects since its unknown how much of any of the ingredients are inside. They also offer a money back return that only works for people who don’t open Phen375, so it’s impossible to use this brand without potentially losing money. Though it’s made in a FDA approved facility which ensures overall quality of the brand, this does not mean that it’s safe or effective.

The product has no real customer reviews, and it’s full of unknown quantities of ingredients.

It also offers a mixture of potentially dangerous ingredients including 2 stimulants that when mixed together has been shown to cause cardiovascular damage in some. Without effective money back guarantee you have to invest a lot of money without a safety or guarantee of quality.

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