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Health Guide Review: 2,7/5


Lipodrene Review: Does it work?

Intro: What is it?

Lipodrene is a weight loss pill made to produce fast and noticeable results. It’s claimed to be able to turn fat into a useful fuel source.

The company claims this is their flagship brand, and they also say it’s Americas number one selling Ephedra based supplement.  According to them, by using this product you’ll be able to get either sexy curves or a shredded physique. Lipodrene recently had a change of ingredients and their new brand is the subject of this review. What kind of an effect does this stimulant heavy supplement have? Is it safe to use? To answer all the important questions you can read this Lipodrene review.

Lipodrene Ingredients

Ephedra Extract 25 mg Senegalia Berlandieri Extract Phenylethylamine Alkaloids Methylsynephrine N-Methyl-B-Phenylethylamine
N-N-Dimethylphenylethylamine Phenylethylamine Phenylethylamine HCI Synephrine HCI Theobromine
Green Tea Extract (45 mg EGCG) Methylhexamine HCI Hoodia Extract Cassia Nomame Extract Naringen
6,7 Dihydroxybergamottin 5-Methoxytryptamine HCI L-5-Hydroxytryptophan Yohimbine HCI Caffeine Anhydrous 100 mg
Dextrose Microcrystalline Cellulose Hydroxypropyl Methylcellulose Stearic Acid Magnesium Stearate
Sodium Starch Glycolate Starch Triacetin Titanium Dioxide FD&C Yellow # 5 Aluminum Lake
Silica Yellow # 6 Aluminum Lake

 Ephedra Extract: A version of Ephedra which is not as powerful as the now banned full version of Ephedra. Not much information exists about this particular strain. It’s unknown what a safe or effective dose is. Ephedra was banned after there were reports of heart attacks and strokes.

Phenylethylamine Alkaloids: Influences the release of dopamine and serotonin to provide a sense of happiness. It’s not well absorbed by the body and according to it’s:

“rapidly broken down into inactive components”

Since it does not properly metabolize in the body, it’s unlikely to produce any effects.

Methylsynephrine: A form of bitter orange which is a stimulant that raises blood pressure. It’s often added as a weight loss ingredient, though it has been shown to promote side effects:

  • Rapid heart rate and cardiovascular damage.
  • Difficulty breathing and chest pains.
  • Anxiety and paranoia.
  • Cold sweats and feelings of warmth.
  • Muscle twitching and tremors.
  • Insomnia and restlessness.

Senegalia Berlandieri: Shrub that has alkaloids including amphetamine, methamphetamine, nicotine, and mescaline.  I couldn’t find one study which revealed whether or not it’s safe or effective.

Amphetamine like substances has been shown to produce side effect such as:

  • Rapid heart rate and irregular heart rhythm.
  • Mood swings and feelings of depression.
  • Muscle twitching, jitters, and spasms.
  • Withdrawal symptoms including headaches.
  • Allergic reactions including rashes and itching.
  • Nausea, vomiting, diarrhea, and feelings of sickness.

Phenethylamine: Chemical used for its stimulant and drug like effects. It’s known to cause amphetamine like changes.  Possible side effects are:

  • Agitation and mood swings.
  • Rapid heart rate.
  • Changes in mood including depression and anger.
  • Nausea and vomiting.

Theobromine: Extract most commonly found in chocolate. It’s used to increase blood flow and widen blood vessels. Too much can lead to Theobromine poisoning which leads to:

  • Seizures, muscle spasms, and twitching.
  • Irregular heartbeat, rapid heart rate, and rapid increase in blood pressure.
  • Internal bleeding.
  • Chest pain and pressure in the chest area.
  • Nausea, vomiting, and ill feelings.
  • Death

Methylhexanamine HCL:  Stimulant energy booster made that’s most widely known as DMAA. Once healthy people have died from supplementing with this, and according to the FDA it can lead to:

shortness of breath and tightening in the chest (as well as) heart attack”

It’s banned in the US, UK, Brazil, Canada, New Zealand, Australia, Sweden, and other countries. Many sports organizations have banned this from use as well.

It’s considered a potentially dangerous additive of which its negatives outweigh nay potential positives.

5-methoxytryptamine: Hormone produced after the body processes tryptophan. The US National Library of Medicine released a study which showed it lead to:

“body shakes and limb jerks”

“behavioral changes:


It’s sometimes used as an alternative to drugs since it can be found in the wild.

Yohimbine HCL: Taken from a tree bark, it’s used to promote fat burning but this effect has only been shown when fasting. It’s known to have an increased risk for causing anxiety. Potential side effects may include:

  • Rapid heart rate and cardiovascular damage.
  • Anxiety and irritability.
  • Mood swings.
  • Insomnia and restlessness.
  • Tremors and muscle twitching.

FD&C Yellow # 5 Aluminum Lake: Food coloring that in some is an extreme allergen. This can lead to:

  • Rashes and itching.
  • Bronchial asthma.

There’s also no nutritional value to this food coloring, it’s been criticized by groups as being a potential carcinogen.

FD&C Yellow # 6 Aluminum Lake: Food coloring with levels of benzidine, a carcinogen.  A study published in the National Library of Medicine declared that:

ingestion of free benzidine raises the cancer risk”

Organizations including the Center for Science in the Public Interest have petitioned the FDA to ban this specific food coloring.  It’s also shown to increase hyperactivity in children.

Lipodrene Quality of Ingredients

There’s a huge amount of stimulants added to this formula including additives such as Methylsynephrine, Synephrine, Theobromine, Caffeine, Senegalia Berlandieri, Yohimbine, and PEA. All of which have been shown to be potentially harmful on their own.

The company does not provide any evidence that taking this mixture is either safe or effective. Most studies show that some of these ingredients on their own can produce serious side effects.  It’s unknown what kind of a total impact the entire formula may have.

The Price and Quality of Lipodrene

Direct sales are offered from the company for a 100 capsule bottle retailing at $69.95. The maximum is 4 capsules a day, which means the daily price, is equal to:

$69.95/25= $2.79 for one full daily serving.

There is a high amount of stimulants, potentially harmful food colorings, and no signs of a money back guarantee. It’s unknown if this brand is safe to use in the long term as well, as no proof is provided that this has been tested.

High Level of Stimulants

Mixing stimulants can increase the overall effects of each, and it’s unknown what kind of effect this brand may have. mentions that Yohimbine when mixed with other stimulants needs to be taken slowly since:

two supplements can interact negatively”

When using a mixture of stimulants it’s important to look at clinical studies, of which none exist on the ingredients featured in this blend.

The company also fails to provide any proof to suggest this brand is either useful or safe.  It’s unknown what kind of a total effect this may have.  They’ve claimed that using this brand is great for weight loss, and it’s supposedly Americas number 1 selling ephedra based supplement, though no evidence is provided to back up these claims.

One full dose provides 400 mg of caffeine which is advised as the daily limit for the average person. When mixing the highest recommended limit with Synephrine, Yohimbine, PEA, DMAA, and other ingredients, there’s no way to judge what kind of an impact it may have on the body.

Business of Lipodrene

Hi-Tech Pharmaceuticals makes Lipodrene and they can be found below:

Phone Number: (888) 855-7919

Address: 6015 B Unity Drive

Norcross, Georgia 30071

The company has had several issues with both the FDA and FTC over the safety and weight loss claims made of their supplements:

  • Previous batches of Lipodrene had levels of Acacia Rigidula which has been shown to contain levels of BMPEA. According to the FDA this ingredient has no proof to suggest whether it’s either safe or effective. The company tried fighting back by claiming it was safe to use, but this was denied. Several 3rd party retailers still sell old versions of Lipodrene with these now banned substances.
  • The FDA took over $2 million in products containing the banned substance DMAA. The company claims no side effects were possible, but studies show DMAA can produce cardiovascular damage and even death.
  • The FTC filed a lawsuit claiming the company would make many unproven weight loss claims about their brand. The FTC fined the company $40 million for their sole in making false claims.
  • The owner of this company was fined $16 million for the lack of proof on 3 of the company’s supplements.

Customer Opinions of Lipodrene

There were reviews of the old formula of Lipodrene, but none for the new version. It’s unknown when they started making different batches, but this brand does contain many of the same ingredients except for Acacia Rigidula.

Still, it’s impossible to determine what kind of an effect this new version will have.

Previous batches were largely unsupported by customers, many of which claimed there were extreme side effects including rapid heart rate, jitters, and insomnia.


 Many things need to be considered about Lipodrene:

  • The company has failed to provide any proof of safety or quality: It’s important to determine exactly what kind of research went into the making of this brand. When mixing stimulants the effects are increased up to sometimes twice as much. Though there have been negative clinical studies showing the effects of bitter orange and caffeine, though it’s unknown what the entire list of ingredients have to offer. There are ingredients in here such as potential allergens in food coloring, as well as high amounts of stimulants. Without being able to look at the data on what’s to be expected, you won’t be able to determine a likely result of Lipodrene. No money back guarantee is offered either, so all sales are final.
  • It’s unknown what kind of an effect these stimulants may have: There’s no clinical study performed on what kind of an effect the formula in Lipodrene might have. The company does claim its effective for weight loss, and they also suggest it’s made to make people shredded. Without being able to look out how they came to these conclusions, there’s no reason to believe what they have to say is true. They also mention this brand is their number one selling weight loss product and that billions have been sold. This is possibly exaggerated since there aren’t many reviews available online for their old formula.
  • No customer reviews are available for the new formula: The manufactures do not provide any of their own testimonials or clinical studies. Older reviews for the original formula were largely negative, with many claiming they experienced difficult side effects including insomnia, rapid heart rate, and anxiety. These are all common features that are possible from supplementing with this mixture of stimulants. No new reviews means it’s impossible to judge whether or not this brand is actually beneficial, or if the old reported side effects are still common.
  • The FDA and FTC have fined this company repeatedly: This has been a major issue with the company and they’ve been fined millions. The company has been warned numerous times as well for making brands like Lipodrene. This brand was specifically targeted for containing amounts of BMPEA, which the FDA noted could lead to stroke and even death. The company tried claiming it was safe to use, and that they’ve never received any health warnings. However, the FDA disagreed and continued to keep it banned. This is why the new formula of Lipodrene exists; it got rid of the potentially harmful additive. However, it still has a high amount of stimulants which may be potentially harmful.
  • They’re currently in court over false weight loss claims: The FTC has fined the company millions for making false weight loss claims. Since the trail is ongoing its unknown if Lipodrene is one of the supplements targeted. However, until more information is revealed about the trial, it’s unknown if what the company clams is true. They don’t offer a money back return on Lipodrene, and they fail to provide any testimonials or proof of safety and effectiveness.

Due to there being no proof provided by the company, and a current FTC lawsuit against their weight loss claims, it’s unknown what kind of an effect this brand may have.

No clinical studies are offered and it’s unknown what kind of total effect the stimulants may have. There are several potentially damaging ingredients that may cause severe side effects.

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